PAM是特别为关节疼痛的机械刺激和评估而设计的,它直接应用了一个被量化的力,且直接读出受试动物的反应。
实验操作人员只需在自己一大拇指套上一个特制的力传感器,仪器将记录受试动物的受力过程,直至动物挣扎。仪器配备了两个力传感器,分别用于大鼠和小鼠。
该仪器包含一个有内置记录功能的控制系统和一个新的DCA软件用于信号检测、数据分析和转换。数据保存以后,可以在控制系统上浏览,也可以转换成Excel或者txt文件保存在电脑里,以便数据分析处理。
PAM是测量机械痛阈的新型工具,是专为关节炎研究设计的,特别适合用于啮齿类动物膝或足踝关节的疼痛评估;此外,配备一个爪压力传感器后,该仪器也可用于大小鼠爪的痛觉研究。
PAM是特别为关节疼痛的机械刺激和评估而设计的,它直接应用了一个被量化的力,且直接读出受试动物的反应。
实验操作人员只需在自己一大拇指套上一个特制的力传感器,仪器将记录受试动物的受力过程,直至动物挣扎。仪器配备了两个力传感器,分别用于大鼠和小鼠。
该仪器包含一个有内置记录功能的控制系统和一个新的DCA软件用于信号检测、数据分析和转换。数据保存以后,可以在控制系统上浏览,也可以转换成Excel或者txt文件保存在电脑里,以便数据分析处理。
特征 | 优点 |
力直接作用于关节 | 直接测量诱发疼痛 |
专为关节炎研究设计 | 传感器着力点外形根据啮齿类动物关节制造 |
可选配爪压力传感器 | PAM 也可作为一台手持的压痛仪使用 |
分辨率: 0.1g
最大适用力:1500g
净重:1.4Kg
毛重:2.7Kg
包装规格:46x38x27cm
Arthritis is associated with chronic, debilitating pain in the joints. Current metrics of arthritic pain in animal models are indirect, by scoring the level of motor activity or the animal weight distribution (Barton et al. 2007); while correlating well with the level of joint pain, their metric is a composite picture of complex pain responses, and provides little direct information about local stimulation and locally-evoked responses.
The quantification of localized joint hypersensitivity is not common in animal experiments; in this sense the PAM device represents a step forward toward multifactorial measurement of pain-related behavior in animal research; the PAM is the first instrument designed specifically to apply force to the joint and automatically detect the animal response.
38500 PAM压力测量系统包含如下部件
38500-001 电子元件
38500-002 大关节传感器
38500-003 小关节传感器
38500-011 DCA软件
38500-302 说明书
38500-303 脚踏开关
选配
38500-006 抓力传感器
38550 PAM高压型,为大型动物设计
净重:1.5Kg 毛重:2.7Kg 包装规格:46x38x27cm 总重量:约27.50 Kg
{module Bibliography on 38500}
Acknowledgements:
The PAM device was invented and validated in the University of Edinburgh by the team of Prof. Daniel McQueen, Susan Bond and colleagues and Dr. Harry Brash, who built the first prototypes.
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