条件恐惧系统（新版）

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附加信息

主要特点：
在黑暗状态中也可以自动识别冻结状态  
有不同型号用于匹配大、小鼠    
多个组合实验笼设计（最多16个笼子，4个组）     

2014新版本：
新的应用程序“launcher”使得不同的UB的行为笼能够被一台触屏控制器40500-001操控，仅需一台硬件设备和特定的软件。
远程控制使得远程服务和软件升级变得十分快捷。

新的条件恐惧系统控制器46000-100，在一个电子部件里包含了所有的控制元件。

研究人员可在舒适的12寸的触屏上设置以下参数。
声音：在100Hz-40KHz; 1-150dB 或白色噪音范围内设置，发声器含在隔间内。
电击：连续的电击强度，（从0.1 到 2.9 mA，每0.1mA 递增），电击强度能够通过外置的控制键操控（通过5VTTL信号 ）
动物箱电气网格地板
46003小鼠实验箱，内径17x17x25(h) cm
46002大鼠实验箱，内径26x26x30(h) cm
型号规格：
动物笼隔间 55(d) x 60(w) x 57(h) cm
控制器 25(d) x 33(w) x 5.5(h) cm
小鼠笼 21(d) x 24(w) x 30(h) cm
大鼠笼 30(d) x 34(w) x 41.5(h) cm
尺寸：每个实验笼设备 79x61x75
净重：每个实验笼设备35Kg
毛重：每个实验笼设备约42Kg

Fear Conditioning is a quick and reliable method to assess memory in rodents.

When rodents are exposed to fearful stimuli, they respond, among the others, with immobility behavior, also called “freezing”. All different Fear Conditioning procedures imply the measurement of the freezing response (i.e. the fraction of time spent immobile).

A rodent can learn to fear a previous neutral stimulus if that has been associated with an instinctively aversive one (such as an electric shock), or, in other terms, after having been conditioned.

After the conditioning has occurred, and the two stimuli have become associated, the animal is presented the neutral stimulus and, as a consequence, it will freeze. Freezing is commonly defined as complete immobility, apart from respiratory movements.

The time spent freezing is indicative of undergone memory and learning processes, which are at the basis of the association between neutral and aversive stimuli.

Fear Conditioning is a sensitive and quick test, which requires very little training (usually only one trial) to the animals. It is therefore a valuable tool for basic behavior research, as well as for high throughput and drug discovery studies. Moreover, the conditioning established during the Fear Conditioning procedure can be very strong (i.e. long-lasting), allowing for long term experiments.

 

完整的系统包含软件和摄像头
小鼠 
46153 完整单笼条件恐惧系统
46253 完整两笼条件恐惧系统
46453 完整四笼条件恐惧系统
大鼠    
46152 完整单笼条件恐惧系统
46252完整两笼条件恐惧系统
46452 完整四笼条件恐惧系统

基础系统，不含软件和摄像头 
小鼠
46103 单笼条件恐惧系统
46203 两笼条件恐惧系统
46403 四笼条件恐惧系统
大鼠
46102 单笼条件恐惧系统
46202两笼条件恐惧系统
46402 四笼条件恐惧系统

附加的组合包括，动物笼，扩张隔间和电子原件(没有相机)
46102-002 大鼠
46103-003 小鼠

所有的配件都能够单独订购

{module Bibliography on 46001}